Diet and risk of gastro-oesophageal reflux disease in the Melbourne Collaborative Cohort Study

SE Wang; AM Hodge; SG Dashti; SC Dixon-Suen; H Mitchell; RJS Thomas; EM Williamson; E Makalic; A Boussioutas; AM Haydon; GG Giles; RL Milne; BJ Kendall; DR English

Journal article

Diet and risk of gastro-oesophageal reflux disease in the Melbourne Collaborative Cohort Study

SE Wang, AM Hodge, SG Dashti, SC Dixon-Suen, H Mitchell, RJS Thomas, EM Williamson, E Makalic, A Boussioutas, AM Haydon, GG Giles, RL Milne, BJ Kendall, DR English

Public Health Nutrition | CAMBRIDGE UNIV PRESS | Published : 2021

DOI: 10.1017/S1368980021000197

Abstract

Objective: To examine associations between diet and risk of developing gastro-oesophageal reflux disease (GERD). Design: Prospective cohort with a median follow-up of 15·8 years. Baseline diet was measured using a FFQ. GERD was defined as self-reported current or history of daily heartburn or acid regurgitation beginning at least 2 years after baseline. Sex-specific logistic regressions were performed to estimate OR for GERD associated with diet quality scores and intakes of nutrients, food groups and individual foods and beverages. The effect of substituting saturated fat for monounsaturated or polyunsaturated fat on GERD risk was examined. Setting: Melbourne, Australia. Participants: A coh..

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University of Melbourne Researchers

Allison Hodge Author

Ghazaleh Dashti Author

Robert Thomas Author

Enes Makalic Author

Related Projects (3)

Epidemiology of chronic disease, health interventions and DNA studies

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Grants

Awarded by Cancer Council Victoria

Funding Acknowledgements

The Melbourne Collaborative Cohort Study (MCCS) cohort recruitment was funded by VicHealth and Cancer Council Victoria. The MCCS was further augmented by Australian National Health and Medical Research Council grants 209057, 396414 and 1074383 and by infrastructure provided by Cancer Council Victoria. Cancer cases and vital status of participants were ascertained through the Victorian Cancer Registry and the Australian Institute of Health and Welfare, including the National Death Index and the Australian Cancer Database. The study of gastro-oesophageal reflux was funded by NHMRC project grant (504708). S.W. is supported by an Australian Government Research Training Program Scholarship.